Physiologically-based Pharmacokinetic (PBPK) Modeling

Tuesday, June 7, 2022
10:00 am - 2:00 pm ET (US)

Session 1: Mechanistic Modeling of PK in Special Population
Chairs: Yuan Chen, Genentech, and Oliver Hatley, Certara UK Limited, Simcyp Division

10:00 am - 10:05 am | Welcome and Introduction

10:05 am - 10:35 am | Keynote Lecture: Overview of Special Population, Physiology, Proteomics of Enzymes and Transporters
Jashvant Unadkat, University of Washington, Seattle, Washington, USA

10:35 am - 10:55 am | Organ Impairment PBPK
Tycho Heimbach, Merck & Co., Inc, Rahway, New Jersey, USA

10:50 am - 11:10 am | Pediatric PBOB (IQ Pediatric Work)
Wen Lin, Janssen R&D

11:10 am - 11:25 am | Break

11:25 am - 11:45 am | Regulatory Perspective on PBPK Modeling of Special Populations
Ying-hong Wang, U.S. Food and Drug Administration, Silver Spring, Maryland, USA

11:45 am - 11:55 am | Selected Abstract Presentation
To be determined

11:55 am - 12:05 pm | Selected Abstract Presentation
To be determined

12:05 pm - 12:35 pm | Roundtable Discussion with Speakers

12:35 pm - 12:40 pm | Session Closing Remarks

12:40 pm - 1:00 pm | Break

1:00 pm - 2:00 pm | Poster Session 1